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Still, there are some limitations, such as involving a small number of patients depending on subjective yet acceptable scores rather than objective scores, a lack of positive control groups, or a small number of patients

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35 Although safe and effective at therapeutic doses, an overdose of APAP can cause severe liver injury, acute liver failure, and even death

doi: 10.3390/pr9020356 34 HanH.XingJ.ChenW.JiaJ.LiQ