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120 Currently, research on D-Asp as a treatment for TRS disease is still in its early stages, and animal experiments are ongoing

R 1 relaxation rates observed in free p53 194 and in complex with FOXO4 FH are highly similar indicating that the sub-ns motions and rotational tumbling of p53 194 are only slightly affected by FOXO4 FH binding (Supplementary Fig

Our findings point to expression changes in 30 genes attributable to the genetic alteration in Glud1 , and no changes induced by stress exposure alone

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Future research should focus on further optimisation of these analogues, exploring formulation strategies that maximise absorption and therapeutic effectiveness