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J Clin Invest 86 : 265272 Mauras N and Haymond MW (2005) Are the metabolic effects of GH and IGF-I separable
Overall, we have determined multiple structures of human CBS, showing that the full-length enzyme polymerises as an active filament that changes conformation due to SAM

Similar results were obtained in AGS5 patients cells (Fig

& Hollien, J
The reported general prevalence and incidence range from 0.5 to 27.9/100,000 and 0.2 to 8.8/100,000, respectively, and the diseases prevalence seems to be rising, particularly in people over 65 [2, 3]

The downstream consequences of this oxidative stress are catastrophic for cellular energy production