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actual product may vary Cyanocobalamin is a vital man-made form of vitamin B12, crucial for treating B12 deficiency

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Endocrinology 142 : 51825189 Hollenga C et al

doi: 10.2337/db10-0805

Worked as decribed

It is possible the human trials never delivered enough intact peptide to the relevant tissue to reproduce the rodent effect, though this remains a hypothesis rather than a demonstrated cause of failure