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Proceedings of the National Academy of Sciences

Physician notes ruling out alternative causes
Moreover, the SUSTAIN trials, which studied the effects of semaglutide in those with T2DM, also demonstrated significant improvement in risk factors, with a substantial 26% relative reduction in cardiovascular events such as nonfatal myocardial infarction and stroke [13,14,29]

placebo (mean change from baseline 14.9% vs
doi: 10.1210/endo.143.6.8840
