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Metabolic conditions that increase alpha-cell mass (44) also increase alpha-cell PC1/3 expression (61) and GLP-1 production (41, 75, 86)
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The authors concluded, "Treatment with GLP-1 receptor agonists was associated with lower all-cause mortality among patients with type 2 diabetes, advanced-stage CKD, and ESKD than was treatment with DPP-4 inhibitors
