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Silvana Obici, an endocrinologist and chief of the division of endocrinology at Stony Brook Medicine

Yes low fiber, dysbiosis, or inflammation reduces SCFAs, weakening GLP-1 output and increasing hunger and cravings

Intravenous injection of PYY (3-36) in rats was 10 times more potent in suppressing feeding than an injection of PYY (1-36) and 48 times more potent in suppressing feeding than an intravenous injection of PYY(3-36) in humans (Steinert et al., 2017)

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doi: 10.1038/s41514-018-0029-z