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Approved by the FDA in May 2022, Tirzepatide has quickly gained attention not just for its ability to control blood glucose but also for its unprecedented impact on body weighttwo of the most critical challenges in managing type 2 diabetes

In patients with T2DM, the AKT/PI3K signaling pathway is dysfunctional, contributing to the pathophysiology of this disease [100]

Typically, medications in this class are recommended for individuals with a medical history of type 2 diabetes

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Understanding the relationship between these medications and muscle-related symptoms requires careful examination of available evidence and clinical experience