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Alzheimers Dement (2015) 11:608621.e7

doi: 10.1016/j.joca.2012.11.012

By engaging two hormonal pathways, Tirzepatide improves insulin sensitivity and drives larger reductions in appetite and food intake than single-pathway agents

I think the side effect numbers look intimidating on paper, but the real-world experience is often much milder than people expect

Under normal digestive conditions, small amounts of sugar alcohols cause minimal symptoms
