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In PIONEER-2, oral semaglutide reduced CRP, whereas empagliflozin did not, despite similar weight loss

Pharmacodynamics, pharmacokinetics, safety and tolerability of the novel dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 agonist RG7697 after single subcutaneous administration in healthy subjects

38% relative risk reduction), hospitalization for HF (2.7% and 4.1%, respectively

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SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B