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Exenatide was shown in a murine model of atherosclerosis to increase the collagen content of plaque and decrease MMP-9/MMP-2 activity, thereby helping to stabilise plaque [155]

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These medications work best when used alongside dietary and physical activity changes

doi: 10.3389/fendo.2025.1526468 Received 11 November 2024 Accepted 31 March 2025 Published 28 April 2025 Volume 16 - 2025 Edited by Nigel Irwin, Ulster University, United Kingdom Reviewed by Valentina Caputi, University College Cork, Ireland Victory Ashonibare, Heinrich Heine University of Dsseldorf, Germany Updates Copyright 2025 Li, Qiao, Li, Qin, Xu, Lao, Wang, Fan, Tang and Han

Adipose tissue inflammation and metabolic dysfunction in obesity

What science now makes clear is that obesity is rarely about discipline alone