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Self-Reported Questionnaires administered to gain information on perceived health status, psychological functioning, health behaviors, quality of life (Scale 0-100) [9] Patients have lived with CHD their entire life, and report relatively high QoL Older age, lack of employment, never having married, and worse NYHA functional class (self- reported) are associated with lower QoL Alternative Assessment for Nonverbal Patients: Concerns may come from caregivers or parents May demonstrate behavioral changes: outbursts, changes in feeding/eating habits or weight loss/gain, changes in sleeping patterns , fatigue, low mood, anhedonia Screening should begin early in childhood (early assessment and diagnosis allows for enrollment in beneficial social / developmental programs) Cardiac Neurodevelopmental Outcome Collaborative (CNOC): recommend screenings for various ages and provide suggested screening algorithms

In phase 2 trials, people taking 12mg of retatrutide lost an average of 24.2% of their body weight after 48 weeks

Fonseca V, Madsbad S, Falahati, Zychma MJ, Plutzky J

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These have blood-thinning properties that may amplify Motrins effects