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The metabolic slowdown associated with hypothyroidism can make weight management particularly challenging, even with appropriate thyroid hormone replacement therapy

There is time to discuss whether a GLP-1 makes sense for your specific situation, monitor side effects, manage dose escalations, and adjust if something is not working

Standard titration protocol from clinical trials The Phase 2 NEJM trial used the following escalation schedule for the 12 mg dose group: Weeks 1 through 4: 2 mg once weekly (subcutaneous) Weeks 5 through 8: 4 mg once weekly Weeks 9 through 12: 8 mg once weekly Week 13 and beyond: 12 mg once weekly (maintenance dose) For the 8 mg target dose, the schedule was: Weeks 1 through 4: 2 mg once weekly Weeks 5 through 8: 4 mg once weekly Week 9 and beyond: 8 mg once weekly (maintenance dose) These titration schedules are not suggestions

GLP-1 also stimulates insulin gene transcription and islet cell growth

Typical Weight Loss Timeline Semaglutide results dont happen overnight

Weimbs is finding that keto can actually improve kidney function in people living with CKD