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2017Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
If you stop tirzepatide and wait two weeks (roughly four half-lives) before starting retatrutide, the previous medication will have largely cleared, and you are starting closer to baseline

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Based on human experiments, Holst hypothesized that GLP-1 caused slower emptying of the stomach, which sent a signal through the vagal nerve signifying fullness

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