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Description
GPER deficiency causes increased adiposity, insulin resistance, and metabolic dysfunction in mice (90)

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Diabetic patients have reported experiencing worsening blood sugar spikes and higher blood sugar levels than before they started taking the drug

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Effects of sequential treatment with lixisenatide, insulin glargine, or their combination on meal-related glycaemic excursions, insulin and glucagon secretion, and gastric emptying in patients with type 2 diabetes

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