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You can read the full article Weight Loss and Hypertension in Obese Subjects PMC (nih.gov)

The new results are from a phase 1 trial of a once-daily pill called CT-966, which revealed an average weight loss of 7.3% at four weeks in the study population of obese patients without diabetes, compared to a 1.2% reduction with placebo

These side effects tend to be most prominent at the initiation of therapy and improve with continued use in many patients

Adding filler without first addressing these factors risks puffiness or distortion, particularly in leaner faces

This is especially important if you're very lean or have minimal subcutaneous tissue

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