glp-1 drugs and parkinson's disease How a 'blockbuster' treatment for diabetes obesity might slow or stop – Van Andel Institute GLP-1 drug may help with
Description
British journal of pharmacology

Significance : This trial specifically evaluated semaglutide in individuals WITH type 2 diabetes, demonstrating efficacy and safety in this population

Berberine is the clearest example in human clinical trials

GLP-1R is abundantly expressed in the pancreas and CNS

The studys systematic approachbuilding a detailed atlas of health outcomesprovides a framework for guiding clinical care and future research

Glucagon gene expression in the endocrine pancreas: the role of the transcription factor Pax6 in alpha-cell differentiation, glucagon biosynthesis and secretion
