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compared the use of anti-obesity medications (AOMs), a subset of which were GLP-1 receptor agonists, in 36 IBD patients compared to 36 non-IBD controls and found no significant impact on the frequency of IBD exacerbations (which occurred in 7 patients, 19.4%), defined as the need for steroid use, a change in IBD therapy, hospitalization, and surgery compared to pre-treatment status [37]

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Here's what the long-term evidence actually looks like

Efficacy and Safety of the Once-Daily GLP-1 Receptor Agonist Lixisenatide in Monotherapy: A randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono) Diabetes Care

She has more stamina to chase her kids, tackle gym workouts, and even train for a half-marathon

You can learn more about combining metformin with tirzepatide or metformin with semaglutide in our dedicated guides