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Gottlieb DJ, Punjabi NM

Therefore, the primary aim of this systematic review and meta-analysis is to rigorously evaluate data from available RCTs to determine the effect of GLP-1 RA therapy on key inflammatory biomarkers (CRP, IL-6, TNF-) and the oxidative stress marker (MDA) in patients with T2D

Exercise induces the release of myokines, such as apelin and irisin, alongside increased levels of BDNF ( GLP-1RAs act on overlapping hypothalamic circuits, reducing appetite and improving energy balance and have been shown to promote browning of white adipose tissue, contributing to increased energy expenditure

Panico, C

The evidence supporting this indirect mechanism is strong

Instead of the usual musky smell, sweat may take on a sweet, sharp, or even metallic scent