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However, a loading phase (with 25mg microdoses or 50mg doses) is recommended to minimize side effects

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Discuss with your healthcare provider to weigh the benefits against these considerations, ensuring it aligns with your overall treatment plan

Further, the PI3K/Akt/GSK-3 signaling pathway regulates mitochondrial complex I activity, which is essential for mitochondrial function, energy metabolism, and redox balance (Rai et al., 2019)