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This risk may be higher in people with type 2 diabetes who are taking other diabetes medications, including sulfonylureas

For Phase 1, that is 0.25mg

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Last reviewed: June 9, 2026 Last updated: June 9, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

There have been reports of acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, in patients taking tirzepatide during premarketing trials