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Regarding newer agents, evidence from phase 2 trials indicates that the triple agonist retatrutide (GLP-1R/GIPR/GCGR) can achieve unprecedented weight loss of up to 24.4% (Jastreboff et al., 2023)

In summary, the presence of numerous adenomatous nodules in a background of lymphocytic thyroiditis in younger patients should raise the suspicion for the diagnosis of PHTS

2 3 How do I administer my medication

Losing more than one to two pounds per week consistently, or losing significant amounts of muscle mass, suggests that the appetite suppression may be too aggressive

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Aim for at least 810 glasses of water daily, spread throughout the day