tirzepatide ophthalmic side effects What ODs Need to Know About GLP-1 Drugs Semaglutide or Tirzepatide and Optic

Early data are promising: retatrutide, a leading candidate in this class, produced 24.2% average weight loss at 48 weeks in a Phase 2 trial, exceeding results seen with current medications

Side effects are broadly similar, with tirzepatide more often linked to nausea and vomiting, and semaglutide more to constipation and reflux

Ghusn, W

These benefits stem from tirzepatide dual GIP/GLP-1 mechanism affecting receptors throughout the body

In another notable case, a 36-year-old woman with depression and binge-eating disorder experienced a dramatic improvement in her PHQ-9 score, dropping from 14 to 1, alongside nearly 50 pounds of weight loss over five months on tirzepatide (titrated to 7.5 mg)

Zepbound is the first medication ever approved for OSA in adults with obesity