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Statistical analysis The planned sample size of 495 participants was estimated to provide over 80% statistical power to detect a difference between any active treatment group and placebo with respect to the primary endpoint using a two-sided t -test with significance level of 0.05

It is associated with obesity, smoking and pregnancy

Statements Author contributions BG: Writing original draft

They are interested in exploring this effect further, considering its potential benefits for patients with alcohol dependency issues

Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes

Things are different now that they're both taking an obesity drug