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Medication enters the body through a small injection, which allows steady absorption and reliable dosing

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November 2025: FDA approved expanded Zepbound (tirzepatide) indication for moderate-to-severe obstructive sleep apnea in adults with obesity, following SURMOUNT-OSA trial data showing 62.8% reduction in apnea-hypopnea index the first drug approval for sleep apnea treatment

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They showed that organ bath studies identified a role of GLP-1R in the regulation of smooth muscle function by influencing the basal tone in colonic muscle strips and mediating relaxation of acetylcholine-induced phasic and tonic contractions in the colon

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