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A 2023 study shows that semaglutide, a GLP-1 agonist, reduced cardiovascular events by 20%, while other studies show that the Mediterranean diet can reduce heart disease by up to 30% for those at risk 7,8,9

Currently, the agency only allows compounded drugs which are typically significantly cheaper during a shortage or in specific cases where certain patients arent able to use FDA-approved drugs

Tirzepatide Cons: Cost is greater than Semaglutide

In a large phase 3 obesity trial (ACHIEVE-1), orforglipron at daily doses of 3, 12 and 36 mg caused approximately: Diarrhoea: 1926% of participants (vs 9% on placebo) Nausea: 1318% (vs 2% on placebo) Constipation: 817% (vs 4% on placebo) Vomiting: 514% (vs 1% on placebo) Across multiple studies, 617% of people stopped treatment because of side effects, mostly gut-related symptoms

Liraglutide offers proven reliability, while Semaglutide pushes boundaries with groundbreaking results in weight reduction and glucose control

Reconstitution Process: Lyophilized peptides require reconstitution before use