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Sleep, Stress, and Hormones Research associates short sleep (under 7 hours) with higher levels of ghrelin (a hunger hormone) and lower levels of leptin (a hormone that signals fullness)

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Anti-Inflammatory Effects Chronic inflammation is a common underlying factor in many metabolic disorders, including diabetes

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Because it is metabolized primarily in the liver without the formation of active metabolites, glipizide is the preferred sulfonylurea in patients with renal disease (40)