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"The side effects for metformin are usually milder, and they resolve with time or by eating some food," Horn says
iv) Modulation of adipokine secretion: Weight loss and adipose tissue reduction induced by GLP-1RAs alter adipokine secretion profiles, for example by shifting adiponectin- and leptin-related signals, which can directly influence tumor cell proliferation and invasion (69,131)
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Balazs also mentioned the psychological burden of obesity and diabetes, noting that weight-loss therapies can alleviate depression and anxiety, conditions that often contribute to sexual dysfunction
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