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Description
In one of the studies, patients with a mean baseline body mass index (BMI) of 35.3 kg/m and an average HbA1c of 8.3% were randomized to receive varying doses of GLP-3 (ranging from 1 mg to 12 mg) or placebo over a 36-week study period

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4 The ACC document additionally provided a series of opportunities in which clinicians may consider starting a GLP-1 RA or an SGLT-2 inhibitor with demonstrated cardiovascular benefit 4 : In a patient with T2D and ASCVD
They have also come with significant side effects, significant cost ($149 to $349 per month and climbing), and now a daily pill version that still requires a prescription, a doctor's visit, and a long-term financial commitment
This is a promising and innovative route toward the development of unimolecular peptide drugs with superior efficacy than those currently available for the treatment of obesity and T2DM

Your dose may need to go up, but your price won't, making it predictable to budget for your weight loss therapy
