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In the Brain: GLP-1 decreases appetite, increase satiety and energy production

Metabolic and hormonal adaptation Starting a GLP-1 treatment can cause a shift in how the body regulates appetite, how it digests food, and can affect blood sugar levels and metabolism

Lilly submitted the diabetes NDA in October 2021, the FDA approved Mounjaro in May 2022, and the obesity approval (Zepbound) followed in November 2023

This one-week adjustment prevents unnecessary disruption to your routine while giving your body the gentlest possible introduction to each new dose level

But theyre not FDA-approved to treat hypertension (high blood pressure)