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Mitigate risks of therapy discontinuation

Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis

Here's a realistic clinical picture: semaglutide and tirzepatide have substantial clinical evidence as prescription weight-management tools for eligible patients when prescribed and monitored by qualified healthcare professionals

Creates a feeling of fullness, preventing overeating

This is made worse by spicy/acidic food and drinks

Trulicity Other medication options If youre thinking about stepping off GLP-1s entirely, there are several nonGLP-1 medications that may still offer help with appetite and metabolism