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Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus

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The STEP trial data shows that the cumulative incidence of gastrointestinal adverse events peaks around week 20 and plateaus thereafter

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doi: 10.1002/mds.25945 81 KouliATorsneyKMKuanW-L

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Neurodegeneration models require integrated brain-body systems that no current NAM replicates

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This can then be continued when semaglutide is stopped to help prevent weight gain

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Massive benefit just on patient convenience there with the half-life being so much longer

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