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Unregulated or improperly used GLP-1 drugs can cause anxiety, mood changes, and in some cases, worsen depression or eating disorder symptoms especially in individuals with pre-existing mental health conditions

Also, due to the important role of endothelial dysfunction in CVD, the effects of GLP-1RA on flow-mediated vasodilation (FMD) in patients remain to be investigated for their contribution to the CVD actions of GLP-1RAs

Its FDA-approved for type 2 diabetes and obesity

These efforts, along with implementing diet and lifestyle changes, will provide the most effective and sustainable outcomes and help inform the decision of whether to use medications or not.

The lowest doses produced the smallest increases

Semaglutide is a pure GLP-1 receptor agonist: it mimics glucagon-like peptide-1, a hormone your gut releases after eating