how to manage glp-1 side effects Struggling with therapy effects? You're not alone. This Clinician Guide: Managing Common GLP-1 Receptor Agonist Side provides practical tips on recognizing, preventing and managing gastrointestinal and nutritional side effects glp 1 drug side effects
Description
In a large phase 3 obesity trial (ACHIEVE-1), orforglipron at daily doses of 3, 12 and 36 mg caused approximately: Diarrhoea: 1926% of participants (vs 9% on placebo) Nausea: 1318% (vs 2% on placebo) Constipation: 817% (vs 4% on placebo) Vomiting: 514% (vs 1% on placebo) Across multiple studies, 617% of people stopped treatment because of side effects, mostly gut-related symptoms
Diabetes 59 , 17651770 (2010)
Qual Life Res
Notably, Kyriakidou et al
dehydration leading to kidney problems
10.1038/mp.2010.80 [DOI] [PubMed] [Google Scholar] Maes M., Leonard B
