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Fee applies to treatment

Employing HITI for in vivo knock-in of large DNA fragments, we designed a guide RNA (gRNA) targeting exon 14 of the Alb gene (sgAlb-E14), which has demonstrated efficient ectopic gene integration via genome editing 20

[DOI] [PMC free article] [PubMed] [Google Scholar] 92.Luna-Marco C., de Maraon A.M., Hermo-Argibay A., Rodriguez-Hernandez Y., Hermenejildo J., Fernandez-Reyes M., Apostolova N., Vila J., Sola E., Morillas C., et al

The therapeutic potential of GLP-1R and its agonists has reshaped approaches to managing type 2 diabetes mellitus (T2DM), cardiovascular diseases, obesity, and even neurodegenerative conditions

But given the strength of the trial data, it's a development worth watching closely

doi: 10.1016/J.EJPHAR.2017.07.015