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Description
A limited exception to market exclusivity exists for drugs on the FDAs shortage list, which indicates a drug in low supply

This acquisition is aimed at enhancing its portfolio with the addition of Metsera's Next-Generation Obesity Portfolio.

In clinical trials, GLP-1 RAs were shown to significantly lower blood pressure (BP) in addition to HbA1c and body weight (BW), indicating the possibility as anti-hypertensive medication of type 2 DM individuals

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Results Despite heterogeneity in study designs and populations, a largely consistent association was found between GLP-1RA use and a reduced incidence of glaucoma

For humans, the model-predicted median clearance (CL) and volume of distribution (Vss) of semaglutide were 0.0397 L/h and 6.23 L, respectively
