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restoring GLP-1 function does
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The cheapest total program cost accounting for medication, consultation, and ongoing management fees varies by individual patient situation and provider

For many people, 8 to 12 weeks of manageable diarrhea is an acceptable trade-off for significantly better outcomes

GLP-1RAs have been shown to protect the heart from oxidative stress and reduce the expression of pro-inflammatory cytokines (interleukin (IL)-1, TNF-, IL-6, and monocyte chemoattractant protein-1 (MCP-1)) in the myocardium

The rapid renal clearance of many small peptides like GLP-1, together with its inactivation by DPP4, required development of longer-acting peptides with greater stability and enhanced resistance to DPP-4
