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This is why the titration protocol spaces increases by 4 weeks, to give your body time to adjust before the next step up

Preparing for these social changes is as important as preparing for the physical ones

Packer M, Zile MR, Kramer CM, et al
How does tirzepatide compare to semaglutide for side effects
[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Aronne LJ, Sattar N, Horn DB, et al

So I think it bypasses the gut a little bit and gets absorbed better
