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A drug may improve metabolic risk

Depression in type 2 diabetes mellitus : prevalence, impact, and treatment

This is the hallmark of insulin resistance and a harbinger of diabetes

38 In animal models of obesity, GLP-1 receptor agonists and metformin have been associated with improved sperm parameters and reduced testicular inflammation, oxidative stress or sperm DNA damage

& Yamamoto, M

Effects of miglitol, acarbose, and sitagliptin on plasma insulin and gut peptides in type 2 diabetes mellitus: a crossover study
