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It activates GLP-1 and GIP pathways to slow digestion, reduce appetite and food cravings, and improve blood sugar balance

Because muscle drives metabolic rate, its loss makes weight regain more likely

Targeting obesity, metabolic syndrome, and prostate cancer: GLP-1 agonists as emerging therapeutic agents

Aetna typically requires BMI 30 with a comorbid condition (like hypertension or sleep apnea) or BMI 35 without comorbidities, plus documented diet and exercise failure

295 milliosmoles/L) containing (in mM): 138 NaCl, 5.6 KCl, 2.6 CaCl 2 , 1.2 MgCl 2 , 10 HEPES (adjusted to pH 7.4 with NaOH), and supplemented with 11.1 mM glucose, 20 l ml 1 FBS, 1 l ml 1 Pluronic F-127, and 1 M fura-2 acetoxymethyl ester (fura 2-AM