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In pancreatic function, it serves as a crucial incretin hormone, increasing insulin production in response to oral glucose consumption as opposed to intravenous delivery

doi: 10.1177/1060028014521128

[DOI] [PubMed] [Google Scholar] 19.Davies M., Pieber T.R., Hartoft-Nielsen M.L., Hansen O.K.H., Jabbour S., Rosenstock J

Lastly, they propose that tirzepatide causes a thermogenic-like amino acid profile in BAT, which could explain why obese IR mice have lower systemic BCAA levels [82]

16 On the other hand, the investigational use of GIPR agonists (GIPRAs) has not yielded similar advantages, partly because of a lack of understanding of GIP dose-response actions