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Efficacy of peroxisome proliferator-activated receptor agonists, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors for treatment of non-alcoholic fatty liver disease: A systematic review

Throughout this article, any reference to semaglutide for weight loss refers to Wegovy

Summary: Yes, you can generally take ispaghula husk (Metamucil/Fybogel) safely with Wegovy, as there is no direct contraindication or pharmacological interaction between them
The decrease in activity causes fewer amounts of hormones and peptides to be produced by the thymus

However, enough patients who took Ozempic reported these adverse mental health events that the TGA thought a label change was necessary

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