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Challenges and future directions of CAR-T therapy combined with PD-1/PD-L1 blockade Exogenous co-administration of CAR-T cells with PD-1/PD-L1 inhibitors is conceptually straightforward and clinically accessible

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They found that OLE reduced the liver weights and improved the inflammation and oxidative stress markers, indicating its potential to ameliorate liver damage associated with NAFLD [96]

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doi: 10.1152/ajpregu.00412.2005 75 RezaiePBitarafanVHorowitzMFeinle-BissetC

An enzyme called dipeptidyl peptidase-4 (DPP-4) cleaves and inactivates GLP-1 almost instantly, preventing it from reaching therapeutic targets in any meaningful way