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A 2020 meta-analysis of 12 randomized controlled trials found modest reductions in body weight and waist circumference

LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial Multi-receptor agonists that target the glucagon, glucose-dependent insulinotropic polypeptide (GIP), and glucagon-like peptide 1 (GLP-1) receptors may improve outcomes in type 2 diabetes because this condition is linked to hyperglycemia and obesity

Esta idea represent un avance decisivo ya que durante dcadas la naturaleza de las protenas haba sido motivo de intenso debate en la comunidad cientfica

doi: 10.2337/dc20-S009 6 ArpaiaN.CampbellC.FanX.DikiyS.van der VeekenJ.deRoosP.et al

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