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Description
Tirzepatide targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, enhancing appetite suppression and promoting a broader metabolic response

A strict keto diet is not required, but reducing refined carbohydrates is highly beneficial

A systematic review and meta-analysis evaluating lifestyle-based weight loss interventions in adults with T2D demonstrated their significant efficacy in weight management and glycemic control [358]

The European Medicines Agency said earlier this month that it had begun investigating GLP-1 drugs after Iceland's health regulator flagged three cases of patients thinking about suicide or self-harm
One study revealed a possible protective association between GLP-1 RA and reduced risk of suicidal behavior (HR: 0.27, 95% Cl 0.20 to 0.36) [12]

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