why do you gain weight back after stopping semaglutide How To NOT GLP-1 / (Ozempic, Wegovy, Mounjaro, Zepbound) does the weight come back

SUSTAIN 5: As an add-on to basal insulin vs placebo 1,10 Study design: 30-week, randomized, double-blind, placebo-controlled, parallel-group, multinational, multicenter trial to compare the efficacy and safety of Ozempic injection in combination with basal insulin vs volume-matched placebo in combination with basal insulin

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STEP UP is a 72-week efficacy and safety trial investigating subcutaneous semaglutide 7.2 mg compared to semaglutide 2.4 mg and placebo, all administered once weekly

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Yes, many patients who don't achieve desired results with semaglutide successfully transition to compounded tirzepatide under medical supervision