surmount 5 tirzepatide as Compared with Semaglutide for the Treatment of Obesity: @NEJM π₯Έ SURMOUNT-5 Trial: Wow! π± Summary πππ With respect to the SURMOUNT-MAINTAIN
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Mechanistic data on GLP-1R/GIPR/GCGR tri-agonists The combination of GLP-1RA, GIPRA, and GCGRA in preclinical studies has demonstrated superior weight loss relative to liraglutide in mice with diet-induced obesity, attributed to decreased food intake and increased energy expenditure (Baggio & Drucker 2021)

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Blood sugar levels are also improved, and glucose levels are controlled with this treatment

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