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Exclusion of other causes of neuropathy is crucial for diagnosis, as there are no specific pathognomonic tests for TIND

158,161,164,165 However, activating multiple receptors may lead to more complex side effects, and in some experiments, dual and triple agonists have indeed shown more severe side effects

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If constipation persists despite these measures, speak to your prescriber about possibly pausing dose escalation or temporarily reducing your dose until symptoms improve

School of Public Health and co-Director of the Biostatistics and Data Science Core at UT Southwestern