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Furthermore, in vivo experiments utilizing rotenone-induced mouse model of PD revealed a significant rise in plasma GLP-1 after CGA administration (50 mg/kg, orally for 13 weeks) with concomitant increase in colonic GPR-40 and GPR-43 mRNA expression
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Eli Lillys orforglipron is the first oral non-peptide GLP-1 receptor agonist advancing in obesity and diabetes research
