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Appetite changes can change medication needs

Our research has highlighted that the dysregulated metabolic pathways prevalent in obesity significantly fuel tumor growth and survival, creating an oncogenic environment that diminishes the efficacy of chemotherapeutic agents ( Figure 8 )
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Timing is critical: cramping that begins within days of starting therapy may reflect acute metabolic adjustment, while cramping that emerges weeks later might indicate cumulative electrolyte loss, reduced hydration, or inadequate nutrient intake during weight loss
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Nausea, mild stomach upset or headaches are common side effects
